Motif-based sequence analysis tools
Tutorial and training materials by OpenHelix
| The MEME suite is a freely available collection of tools that can be used to discover motifs in a set of DNA or protein sequences. MEME stands for Multiple Expectation Maximum for Motif Elicitation. With MEME suite you can: discover motifs in DNA or protein sequences; search sequence databases using a given motifs; compare a given motif to all motifs that are in a motif database; and associate motifs with the Gene Ontology terms that are listed for a motifs putative target genes. | Advertisement:
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You'll learn:
- about the different components of the MEME suite, and how they interconnect
- how to discover motifs within DNA or protein sequences
- to align motifs and search for motifs
- to use the MEME suite to search for motif similarity and GO association
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Related tutorialsThis tutorial is a part of the tutorial group Motif analysis tools. You might find the other tutorials in the group interesting:
| Recent BioMed Central research articles citing this resourceKlepper Kjetil et al., MotifLab: a tools and data integration workbench for motif discovery and regulatory sequence analysis Sequence analysis (applications). BMC Bioinformatics (2013) doi:10.1186/1471-2105-14-9 Clark A Tyson et al., Enhanced 5-methylcytosine detection in single-molecule, real-time sequencing via Tet1 oxidation. BMC Biology (2013) doi:10.1186/1741-7007-11-4 Wang Jing et al., Evaluation and integration of existing methods for computational prediction of allergens Selected Articles on Computational Vaccinology The second ISV Pre-conference Computational Vaccinology Workshop (ICoVax 2012). BMC Bioinformatics (2013) doi:10.1186/1471-2105-14-S4-S1 Gautam Ankur et al., In silico approaches for designing highly effective cell penetrating peptides Medical bioinformatics. Journal of Translational Medicine (2013) doi:10.1186/1479-5876-11-74 Dedieu Alain et al., Major soluble proteome changes in Deinococcus deserti over the earliest stages following gamma-ray irradiation. Proteome Science (2013) doi:10.1186/1477-5956-11-3 |
More about the resource:
The MEME suite was originally created by Timothy Bailey from the University of Queensland, Australia and William Stafford Noble from the University of Washington. Currently, the MEME suite continues to be developed and maintained by a group from the University of Queensland, the University of Washington, the University of California at San Diego, the San Diego SuperComputer Center, the NBCR, the CBRC and the National Center for Research Resources.
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